Professor Deb Pal is interested in the genetic epidemiology and mechanisms of childhood epilepsy and its comorbidities. In particular, the common forms of childhood epilepsy with complex genetic inheritance. He heads the BIOJUME study on the genetics of juvenile myoclonic epilepsy; the DESIRE-ELMO study on the predictive use of omics biomarkers in epilepsy-aphasia spectrum; the DOLPHIN study on the assessment of memory consolidation in children; and the CASTLE study comparing sleep modification versus antiepileptic drugs for rolandic epilepsy. In addition, he is supervising two PhD projects on the genetics of myoclonic-astatic epilepsy and the longitudinal imaging correlates of rolandic epilepsy. In his clinical role he leads the Epilepsy Genetics Service at King’s Health Partners.
Role within CASTLE:
Deb is joint lead of the CASTLE programme and the clinical trial itself.
Listen to Deb talk about his role in CASTLE: https://youtu.be/6AeyZb0ggss
Deb graduated in natural sciences and medicine from Cambridge University and holds a Masters in epidemiology from the London School of Hygiene and Tropical Medicine. He completed a PhD in Neuroscience at UCL and postdoctoral training in statistical genetics and genetic epidemiology at Mount Sinai and Columbia University Medical Centers, New York. Prior to joining IOPPN in 2009, Deb was Research Scientist at Columbia University Departments of Psychiatry and Epidemiology.
- Linkage, association and sequence analysis in rare and common disorders
- Epilepsy genetics diagnosis and counselling
- Clinical trials and broad outcomes
- Paediatric Neurology